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4 décembre 2017: 1 événement

  • Séminaires Invités

    Lundi 4 décembre 14:00-15:30 - Guillaume SALBREUX - The Francis Crick Institute, London, UK

    Physics of Epithelial Folding

    Résumé : Three-dimensional deformations of epithelia play a fundamental role in tissue morphogenesis. The shape of an epithelium is determined by mechanical stresses acting within the tissue cells and from the outside environment. Here we introduce a three-dimensional vertex model which allows to represent the shape of a tissue in three dimensions by a set of vertices. In the model, the motion of vertices is set by apical, lateral and basal surface and line tensions, as well as intracellular pressures and external forces. Using this framework, we discuss how patterned force generation in an epithelium can drive biological tissue folding in fold formation in the Drosophila wing disc, and in pancreatic tumour growth.



    contact : Martial Balland

    Lieu : LIPhy, conference room - 140 Avenue de la Physique 38402 Saint Martin d’Hères

    En savoir plus : Séminaires Invités